Substantial Variation in Prostate MRI Interpretation Among Radiologists

From practiceupdate.com
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• Multivariable regression analysis was used to assess the diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) in identifying clinically significant prostate cancer (Gleason score ≥7). The multivariable analysis was adjusted for Prostate Imaging Reporting and Data System (PIRADS) scores, prostate-specific antigen (PSA) levels, age, and radiologist. Detection of clinically significant cancer on fusion-biopsy varied greatly by radiologist. The proportion of “false negatives” (ie, PIRADS ≤2) ranged from 13% to 60% across radiologists.
• Uniform interpretation of mpMRI of the prostate across radiologists cannot be assumed. Institution-specific training for mpMRI interpretation and assessment of internal validity may limit the variability.