Tuesday, July 17, 2018

Perinatal exposure to an environmentally relevant mixture of phthalates results in a lower number of neurons and synapses in the medial prefrontal cortex and decreased cognitive flexibility in adult male and female rats

From the Journal of Neuroscience.

The research was done on rats.  The abstract notes that "Pregnant dams orally consumed an environmentally relevant mixture of phthalates at 0, 200, or 1000 μg/kg/day through pregnancy and for 10 days while lactating."  The definition of "environmentally relevant" is crucial in terms of concentration in the body, particularly in the brain, and whether humans experience the same concentrations.  So, it is impossible to determine from the abstract whether the research is of practical health significance or not.  Nevertheless, it is somewhat worrisome.

Here is a link to a relevant Wikipedia article.

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