Sunday, June 21, 2020

Did Lockdowns really save 3 million COVID-19 deaths, as Flaxman et al. claim?

Here is Nic Lewis at judithcurry.com.

The moral of this story is that a lot of what you hear about COVID-19 from scientists may be wrong.

The paper is quite technical.

Here is the conclusion.
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First and foremost, the failure of Flaxman et al.’s model to consider other possible causes apart from NPI of the large reductions in COVID-19 transmission that have occurred makes it conclusions as to the overall effect of NPI unscientific and unsupportable. That is because the model is bound to find that NPI together account for the entire reduction in transmission that has evidently occurred.

Secondly, their finding that almost all the large reductions in transmission that the model infers occurred were due to lockdowns, with other interventions having almost no effect, has been shown to be unsupportable, for two reasons:
  • the prior distribution that they used for the strength of NPI effects is hugely biased towards finding that most interventions had essentially zero effect on transmission, with almost the entire reduction being caused by just one or two NPI. 
  • the relative strength of different interventions inferred by the model is extremely sensitive to the assumptions made regarding the average delay from infection to death, and to a lesser extent to whether self isolation and social distancing are taken to exert their full strength immediately upon implementation or are phased in over a few days.
It seems likely that the inferred relative strengths of the various NPIs are also highly sensitive to other assumptions made by Flaxman et al., and to structural features of their model. For instance, their assumption that the effect of different interventions on transmission is multiplicative rather than additive will have affected the estimated relative strengths of different types of NPI, maybe substantially so. The basic problem is that simply knowing the dates of implementation of the various NPI in each country does not provide sufficient information to enable robust estimation of their relative effects on transmission, given the many sources of uncertainty and the differences in multiple regards between the various countries.

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